Bring Adhesion Force Measurement to the Next Level
1) Cell culture in a Petri dish or multiwell plate is scanned on a microscope to gain a large mosaic image. 2) Images are analyzed by software to recognize target cells. 3) Selected cells are probed by the micropipette to measure their adhesion force mediated by specific adhesion molecules on functionalized surfaces. 4) Distribution of adhesion force of the cell population. Cells remain intact after the measurement and thus can be used for further analysis, such as DNA/RNA/protein investigations or cloning.
Excellent liquid handling precision: 0.1 nanoliter, with an Outstanding >90% single cell isolation efficiency
High Quality Imaging
Both unlabeled and fluorescent cells can be imaged by high resolution objectives. Sort cells labeled by fluorescent markers or having the desired morphology using computer vision
The number of cells picked in a single run can range from 1 to 1,000
Rita Ungai-Salánki , Published: November 15th 2021
Tamás Gerecsei, Published: January 4th 2021