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Single Cell Immune Profiling 

single cell picking protocol on a microscope

1) Cell culture in a Petri dish or multiwell plate is scanned on a microscope to gain a large mosaic image. 2) Images are analyzed by software to recognize target cells. 3) Selected cells are probed by the micropipette to investigate immune cell adhesion on surfaces decorated by antibodies or ligands of cell surface molecules. 4) Analysis of drug effects on immune cell adhesion.

The Valve Control Technology is a perfect fit to answer your immunology questions.  Analyze antigen specificity, surface protein expression, full length paired B-cell or T-cell receptors and gene expression, all from a single cell.

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precise cell targeting

Unprecedented Precision

Excellent liquid handling precision: 0.1 nanoliter, with an Outstanding >90% single cell isolation efficiency

high quality imaging

High Quality Imaging

 

Both unlabeled and fluorescent cells can be imaged by high resolution objectives. Sort cells labeled by fluorescent markers or having the desired morphology using computer vision

adjustable runs

Adjustable Runs

 

The number of cells picked in a single run can range from 1 to 1,000

Proven Results

Noémi Sándor, Published: September 22, 2016

probing of single immune cells with integrins

Péter K. Jani, Published: July 2016,

probing immune cell adhesion to endothelial cells
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